Abstract:Objective To explore the clinical efficacy of Jieshitong capsule combined with percutaneous nephrolithotomy (PCNL) in the treatment of infectious kidney stones.Methods A total of 120 patients with infectious kidney stones admitted to our hospital from June 2020 to July 2022 were selected as the research objects, and divided into the control group (60 cases) and the research group (60 cases) according to the random number table method. The control group was treated with PCNL and placebo, the study group was combined with Jieshitong capsules on the basis of the control group. The total curative effect erythrocyte immune function[erythrocyte C3b receptor rosette rate (C3bRRR), erythrocyte immune complex rosette rate (ICRRR), tumor red blood cell rosette rate (TER)], postoperative indicators[stones residual rate, time of stone excretion, bowel function recovery time], traditional Chinese medicine(TCM) syndrome score and occurrence of complications of the two groups of patients was recorded and compartd.Results After treatment, total curative effect of the study group were higher than those of the control group, and the C3bRR, ICRRR, TER, the stones residual rate, days of stone expulsion, bowel function recovery time and TCM syndrome scores were all lower than those of the control group (all P<0.05). There was no significant difference in the incidence of complications among patients[13.30%(8/60)vs. 5.00%(3/60),P>0.05].Conclusions Jieshitong capsule combined with PCNL in the application of infectious kidney stones can effectively improve the curative effect, relieve the symptoms of patients, improve the immunity of red blood cells, and promote the recovery of patients after surgery.