Abstract：Objective To systematic evaluation the prognosis factors in patients with benign prostatic hyperplasia (BPH) treated by transurethral surgery.Methods Literatures from CNKI, China Biomedical Literature Database, Wanfang Database, VIP database, PubMed, Cochrane Library, Embase and Web of Science were systematically searched. A cohort study or casecontrol study on prognostic factors of transurethral surgery for BPH from January 1, 1990 to January 25, 2021 was included, and literature quality was evaluated according to Newcastle-Ottawa Scale . Meta analysis was performed using Review Manager 5.3 software.Results A total of 13 literatures were included, including 4 739 patients. The analysis results showed that: preoperative high intracarical prostatic penetration (IPP)（OR=2.25,95%CI:1.20～4.21,P=0.010）, high urinary storage symptom score （OR=0.92,95%CI:0.87～0.96,P<0.001）, advanced age （OR=0.78,95%CI:0.64～0.97,P=0.020）and diabetes mellitus （OR=0.43,95%CI:0.24～0.76,P=0.004） were important factors affecting patients with BPH treated by transurethral surgery.Conclusions Preoperative high urinary storage symptom score, advanced age and diabetes mellitus were risk factors for no improvement of symptoms after transurethral surgery for BPH, and high IPP was protective factor for improvement of symptoms after surgery.
