Abstract：To study the relationship between transrectal ultrasonography(TRUS) examination and β2-microglobulin(β2-MG） detection and clinical stages and disease risk in prostate cancer patients.Methods A total of 120 prostate cancer patients diagnosed from January 2016 to December 2019 in Dongfang oriental hospital of Hainan province were selected as the research subjects, including 62 low-risk patients, 39 medium-risk patients, and 19 high-risk patients. According to Whitmore-Jewett method, the clinical stages of patients were 16 cases in stage A, 39 in stage B, 44 in stage C and 21 in stage D. Ultrasonic ultrasound was compared with different clinical stages and risk patients. The characteristics and the differences between β2-MG were studied. The relationship between disease stages and risk of patients with ultrasound and β2-MG was studied.Results There were statistically significant differences between high-risk, medium-risk and low-risk group, nodules, Vmas, RI, β2-MG (P<0.001). Ultrasound capsule status, nodules, Vmas , RI and β2-MG in stage A, B, C and D patients, the differences were statistically significant (P<0.001). Spearman correlation analysis showed that capsule integrity, nodules were negatively correlated with disease stage and risk (P<0.001). Vmas, RI, β2-MG were positively correlated with disease stage and risk (P<0.001).Conclusions TRUS and β2-MG were significantly correlated with clinical stage and disease risk in prostate cancer patients.
