Abstract：Objective To investigate the effect of microchannel percutaneous nephrolithotomy(mPCNL) and retrograde ureteroscopic lithotripsy in the treatment of diarrhea with diameter<2.0 cm.Methods We selected 90 patients with renal artery calculi who underwent renal calculi from January 2015 to October 2017,45 of whom underwent retrograde ureteroscopic lithotripsy(group A) and sixty patients were treated with mPCNL(group B).The first-stage stone clearance rate,summary stone clearance rate, operation time, surgical bleeding volume, hospitalization time, and surgical complication rate were compared between the two groups. Serum interleukin-6 (IL-6),interleukin-10(IL-10),C-reactive protein(CRP),white blood cells(WBC) and surgical complication rate at 24 hours after surgery were analyzed.Results The first-stage stone clearance rate, summary stone clearance rate, operation time, surgical bleeding volume,and hospitalization time in group B were lower than those in group A(P<0.05).There was no significant difference between group B patients in summary stone clearance rate and group A(P>0.05).The length of hospital stay in group B was longer than that in group A(P<0.05). There was no significant difference in the levels of IL-6,IL-10,CRP and WBC between group A and group B before surgery(P>0.05).The levels of IL-6,IL-10,CRP and WBC in group B were significantly lower than those in group A at 24 hours after operation(P<0.05).There was no significant difference in complication rate between group B and group A(6.67% vs.15.56%,P>0.05).Conclusions The effect of mPCNL and retrograde ureteroscopic lithotripsy in the treatment of patients with inferior sacral calculi<2.0 cm in diameter is not significant, and the inflammatory stress response caused by mPCNL surgery is smaller and the surgical trauma is smaller.
