Abstract:Objective To establish and validate earlywarning scoring system for postinfection after percutaneous nephrolithotomy(PCNL).Methods The expert group was composed of relevant experts from the department of renal surgery,infection department,nursing department, clinical laboratory department, intensive care department and pharmacy department of our hospital.Combined with literature reports,preliminary studies and clinical practical experience, the high-risk factors for postoperative infection of PCNL were determined and assigned, and the earlywarning scoring system was established. The relevant data of 122 cases with kidney stones and the implementation of PCNL in our hospital from January 2017 to January 2019 were retrospectively analyzed to verify the earlywarning scoring system.Results The items of the early warning rating scale included age 65 years old, preoperative urinary tract infection, stone diameter 2 cm, antler stone, and operation time 90 min, and diabetes.Diabetes was further divided into diabetes complications,and the maximum score of the rating scale was 12 points in total. After analysis by mann-whitney U test there was a significant difference in the early warning score between the infected group and the non-infected group(P<0.001). According to the cut off value analysis, the Youden index was the highest at 7,and the early warning score(0-7.0) was divided into the low-risk group, and the early warning score(7.1-12.0) was divided into the high-risk group.The chi-square analysis showed a significant difference in the infection rate between the low-risk group and the high-risk group(P<0.001).Conclusions The early warning rating table constructed in this study is clear,simple and easy to implement,which can help clinical personnel identify high-risk groups of postoperative infection with PCNL.