Objective To investigate the clinical characteristics of adrenal myelolipoma, and improve the level of diagnosis and treatment of the disease. Methods The clinical data of 7 cases of the patients with adrenal myelolipoma were analyzed retrospectively and the literature were reviewed. Results 7 cases received retroperitoneal laparoscopic adrenalectomy. Postoperative pathological examination confirmed the diagnosis of adrenal myelolipoma in all cases. No evidence of recurrence was found within a follow-up of 6 months to 3 years. Conclusion Laparoscopic surgery is safe and effective for adrenal myelolipoma ,and worth clinical promotion because of its minimal invasive and quick recovery.